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SPANXC antibody (AA 21-97)

SPANXC Reactivity: Human ELISA, WB, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN721675
  • Target See all SPANXC Antibodies
    SPANXC (SPANX Family, Member C (SPANXC))
    Binding Specificity
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 21-97
    Reactivity
    • 12
    • 1
    Human
    Host
    • 12
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    This SPANXC antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody may detects SPANX-A, SPANX-B, SPANX-C, SPANX-D
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPANXA
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SPANXC (SPANX Family, Member C (SPANXC))
    Alternative Name
    SPANX (SPANXC Products)
    Synonyms
    C antibody, CT11.3 antibody, CTp11 antibody, SPANX-C antibody, SPANX family member C antibody, SPANXC antibody
    Background

    Synonyms: NAP-X, SPANX, CT11.1, SPAN-X, SPAN-Xa, SPAN-Xb, SPANX-A, Sperm protein associated with the nucleus on the X chromosome A, Cancer/testis antigen 11.1, Nuclear-associated protein SPAN-Xa, SPANX family member A, SPANXA1, SPANXA

    Background: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008]

    Gene ID
    30014
    UniProt
    Q9NS26
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