MAGEB3 antibody (AA 201-300) (Biotin)

Catalog No. ABIN721377

Product Details anti-MAGEB3 Antibody (Biotin)

Target: MAGEB3 (Melanoma Antigen Family B, 3 (MAGEB3))

Binding Specificity: AA 201-300

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEB3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAGEB3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MAGEB3

Target: MAGEB3 (Melanoma Antigen Family B, 3 (MAGEB3))

Alternative Name: MAGEB3 (MAGEB3 Products)

Synonyms: CT3.5 antibody, Smage3 antibody, Mage-b3 antibody, Mage-ps1 antibody, Mage-rs3 antibody, RGD1562343 antibody, MAGEB3 antibody, MAGE family member B3 antibody, melanoma antigen, family B, 3 antibody, melanoma-associated antigen B3 antibody, MAGE family member B5 antibody, MAGEB3 antibody, Mageb3 antibody, LOC509870 antibody, MAGEB5 antibody

Background:

Synonyms: Cancer/testis antigen family 3 member 5, CT3.5, MAGB3_HUMAN, MAGE B3 antigen, MAGE-B3 antigen, MAGEB3, melanoma antigen family B, 3, Melanoma associated antigen B3, Melanoma-associated antigen B3.

Background: MAGEB3 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 % sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.

Gene ID: 4114