MAGEB2 antibody (AA 101-200) (HRP)

Catalog No. ABIN721369

Product Details anti-MAGEB2 Antibody (HRP)

Target: MAGEB2 (Melanoma Antigen Family B, 2 (MAGEB2))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEB2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAGEB2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAGEB2

Target: MAGEB2 (Melanoma Antigen Family B, 2 (MAGEB2))

Alternative Name: MAGEB2 (MAGEB2 Products)

Synonyms: MAGEB2 antibody, CT3.2 antibody, DAM6 antibody, MAGE-XP-2 antibody, MAGE family member B2 antibody, MAGEB2 antibody

Background:

Synonyms: Cancer/testis antigen 3.2, CT3.2, DAM6, DSS AHC critical interval MAGE superfamily 6, DSS/AHC critical interval gene, from MAGE superfamily, 6, MAGE B2 antigen, MAGE XP 2, Mage-b2, Mage-rs2, melanoma antigen family B, 2, Melanoma antigen, family B, 1, Melanoma associated antigen B2, Smage-2 protein, Smage2.

Background: This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 % sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008].

Gene ID: 4113