MAGEA5 antibody (AA 41-124) (Biotin)

Catalog No. ABIN721332

Product Details anti-MAGEA5 Antibody (Biotin)

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Binding Specificity: AA 41-124

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA5 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAGEA5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MAGEA5

Target: MAGEA5 (Melanoma Antigen Family A, 5 (MAGEA5))

Alternative Name: MAGEA5 (MAGEA5 Products)

Synonyms: CT1.5 antibody, MAGE5 antibody, MAGEA4 antibody, Mage-a5 antibody, MAGE family member A5 antibody, melanoma antigen, family A, 5 antibody, MAGEA5 antibody, Magea5 antibody

Background:

Synonyms: Cancer/testis antigen 1.5, Cancer/testis antigen family 1 member 5, CT1.5, MAGE 5 antigen, MAGE 5a antigen, MAGE 5b antigen, MAGE5, MAGEA4, Melanoma antigen family A 5, Melanoma associated antigen 5, MGC129526, MAGA5_HUMAN.

Background: MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene.

Gene ID: 4104