MUM1 antibody (AA 401-500)

Catalog No. ABIN721195

Product Details anti-MUM1 Antibody

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Binding Specificity: AA 401-500

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MUM1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MUM1 antibody (ABIN721195)

Perez-Chacon, Adrados, Vallejo-Cremades, Lefebvre, Reed, Zapata: "Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice." in: Frontiers in immunology, Vol. 9, pp. 3114, (2018) (PubMed).

Target Details for MUM1

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Alternative Name: MUM1 (MUM1 Products)

Synonyms: EXPAND1 antibody, HSPC211 antibody, MUM-1 antibody, IRF4 antibody, 2610019J09 antibody, 9430059D04Rik antibody, UBE-1C2 antibody, melanoma associated antigen (mutated) 1 antibody, PWWP domain-containing protein MUM1 antibody, MUM1 antibody, LOC612320 antibody, Mum1 antibody

Background:

Synonyms: EXPAND1, FLJ14868, FLJ22283, HSPC211, Melanoma associated antigen mutated 1, Melanoma ubiquitous mutated protein, MGC131891, MGC163315, MUM 1, MUM-1, MUM1, MUM1_HUMAN, Mutated melanoma associated antigen 1, Mutated melanoma-associated antigen 1, Protein expandere, PWWP domain containing protein MUM1, PWWP domain-containing protein MUM1.

Background: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Gene ID: 84939

Pathways: Chromatin Binding