MIA2 antibody (AA 268-360)

Catalog No. ABIN721150

Product Details anti-MIA2 Antibody

Target: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Binding Specificity: AA 268-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIA2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTAGE5

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MIA2

Target: MIA2 (Melanoma Inhibitory Activity Protein 2 (MIA2))

Alternative Name: CTAGE5 (MIA2 Products)

Synonyms: MEA6 antibody, MGEA antibody, MGEA11 antibody, MGEA6 antibody, zgc:56047 antibody, melanoma inhibitory activity 2 antibody, CTAGE family, member 5 antibody, CTAGE family member 5, ER export factor antibody, MIA2 antibody, ctage5 antibody, CTAGE5 antibody, Mia2 antibody

Background:

Synonyms: cTAGE 5A, cTAGE 5B, cTAGE 5C, cTAGE 5D, cTAGE family member 5, CTAGE family, member 5, CTAGE5, cTAGE5A, cTAGE5B, cTAGE5C, cTAGE5D, CTGE5_HUMAN, Cutaneous T cell lymphoma associated antigen 5, Cutaneous T-cell lymphoma-associated antigen 5, MEA11, MEA6, Meningioma expressed antigen 6 coiled coil proline rich, Meningioma expressed antigen 6/11, Meningioma-expressed antigen 6/11, MGEA, MGEA11, MGEA6, Protein cTAGE 5, Protein cTAGE-5.

Background: Cutaneous T cell lymphomas (CTCL) represent a group of malignancies that originate from CD4-T lymphocytes and manifest on the skin. CTCL is a general term for several neoplasms including mycosis fungoides, T cell leukemia/ lymphoma and pagetoid reticulosis, all of which are very difficult to treat in the advanced stages. CTAGE2 (cutaneous T cell lymphoma associated-antigen 2) is a member of the cancer/testis antigen family of proteins (CTAGE) that, under normal conditions, are found primarily in the testis with little or no expression in other parts of the body. Another member of the CTAG family, namely CTAGE5 (also known as MEA11, MEA6, MGEA11 or MGEA6), is a tumor associated antigen that is found in tumors of various origins, including cutaneous T cell lymphomas. Both CTAGE2 and CTAGE5 are expressed as multiple isoforms due to alternative splicing events.

Gene ID: 4253