FCRL3 antibody (PE)

Catalog No. ABIN7506112

Product Details anti-FCRL3 Antibody (PE)

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCRL3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu CD307c PE

Specificity: The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: DNA-immunization followed by a boost with CD307c transfected cells

Clone: H5

Isotype: IgG2b kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for FCRL3

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Alternative Name: CD307c (FCRL3 Products)

Synonyms: CD307c antibody, FCRH3 antibody, IFGP3 antibody, IRTA3 antibody, SPAP2 antibody, fcrh3 antibody, ifgp3 antibody, irta3 antibody, spap2 antibody, xfl1.2 antibody, Fc receptor like 3 antibody, Fc receptor-like 3 L homeolog antibody, Fc receptor-like 3 antibody, Fc receptor-like 3 S homeolog antibody, FCRL3 antibody, fcrl3.L antibody, fcrl3 antibody, fcrl3.S antibody

Background: Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3

Gene ID: 115352

UniProt: Q96P31