FCRL1 antibody (PE)

Catalog No. ABIN7506108

Product Details anti-FCRL1 Antibody (PE)

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCRL1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu CD307a PE

Specificity: The mouse monoclonal antibody E3 recognizes an extracellular epitope of CD307a, a transmembrane glycoprotein expressed predominantly on the surface of mature B cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: DNA-immunization followed by a boost with the CD307a transfected cells

Clone: E3

Isotype: IgG1 kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for FCRL1

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Alternative Name: CD307a (FCRL1 Products)

Synonyms: CD307a antibody, FCRH1 antibody, IFGP1 antibody, IRTA5 antibody, A230020G22Rik antibody, Bxmas1 antibody, Bxmh1 antibody, Bxmh1b antibody, Fcrh1 antibody, Fcrh1l antibody, Fcrh1s antibody, Ifgp1 antibody, FCRL1 antibody, MGC148384 antibody, Fc receptor like 1 antibody, Fc receptor-like 1 antibody, Fc receptor-like protein 1 antibody, FCRL1 antibody, Fcrl1 antibody, LOC612035 antibody

Background: Fc receptor like 1,CD307a is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITAM motifs in its cytoplasmic domain. CD307a is expressed mainly on the surface of mature B-cells, and is down-regulated in germinal center B-cells. Expression of CD307a is higher in patients with autoimmune diseases, compared with healthy controls.,FcRL1, FcRH1, IRTA5

Gene ID: 115350

UniProt: Q96LA6