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NG2 antibody (APC)

MCSP Reactivity: Human FACS Host: Mouse Monoclonal 7-1 APC
Catalog No. ABIN7505999
  • Target See all NG2 (MCSP) Antibodies
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Reactivity
    • 45
    • 23
    • 17
    • 1
    Human
    Host
    • 42
    • 14
    Mouse
    Clonality
    • 32
    • 23
    • 1
    Monoclonal
    Conjugate
    • 28
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This NG2 antibody is conjugated to APC
    Application
    • 31
    • 20
    • 10
    • 10
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    Anti-NG2 APC
    Specificity
    The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.
    Purification
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Human bone marrow stromal cells infected with SV-40
    Clone
    7-1
    Isotype
    IgG1
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  • Application Notes
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Alternative Name
    NG2 (MCSP Products)
    Synonyms
    HMW-MAA antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, MSK16 antibody, NG2 antibody, 4732461B14Rik antibody, AN2 antibody, Ng2 antibody, HSMCSGEN1 antibody, MCS antibody, chondroitin sulfate proteoglycan 4 antibody, sperm mitochondria associated cysteine rich protein antibody, CSPG4 antibody, Cspg4 antibody, SMCP antibody
    Background
    Chondroitin sulfate proteoglycan 4,NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.,Chondroitin sulfate proteoglycan 4, MSK16, CSPG4, MCSP
    Gene ID
    1464
    UniProt
    Q6UVK1
    Pathways
    Glycosaminoglycan Metabolic Process
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