SLC44A1 antibody

Catalog No. ABIN7505965

Product Details anti-SLC44A1 Antibody

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC44A1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Anti-Hu CD92 Purified

Specificity: The mouse monoclonal antibody VIM15 recognizes an extracellular epitope of CD92, a 70 kDa transmembrane glycoprotein expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines.

Purification: Purified by protein-A affinity chromatography.

Immunogen: MV4-11 acute myeloid leukemia cells

Clone: VIM15

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for SLC44A1

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Alternative Name: CD92 (SLC44A1 Products)

Synonyms: CD92 antibody, CDW92 antibody, CHTL1 antibody, CTL1 antibody, RP11-287A8.1 antibody, Cdw92 antibody, Ctl1 antibody, 2210409B22Rik antibody, 4833416H08Rik antibody, AW547365 antibody, SLC44A1 antibody, slc44a1 antibody, zgc:112201 antibody, ctl1 antibody, solute carrier family 44 member 1 antibody, solute carrier family 44, member 1 antibody, solute carrier family 44 (choline transporter), member 1a antibody, solute carrier family 44 (choline transporter), member 1 antibody, choline transporter-like protein 1 antibody, Choline transporter-like protein 1 antibody, solute carrier family 44 (choline transporter), member 1 L homeolog antibody, SLC44A1 antibody, Slc44a1 antibody, slc44a1a antibody, slc44a1 antibody, LOC100404101 antibody, chtl-1 antibody, slc44a1.L antibody

Background: Solute carrier family 44 member 1,CD92 is a 70 kDa protein with ten transmembrane domains, intracellular N and C teminus, and two glycosylated larger extracellular loops. In the C-terminal domain, there is an ITIM-like sequence. This protein seems to be a choline transporter responsible for delivery of choline into the immune cells, to make it accessible for phospholipid synthesis, as well as a regulator of immune cell signaling. It is expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines. It can also be found on mast cells (but not eosinophils), and weakly on peripheral blood lymphocytes, fibroblasts, epithelial cells, and endothelial cells.,CTL1, CHTL1, SLC44A1

Gene ID: 23446

UniProt: Q8WWI5