CD41, CD61 antibody (PerCP)
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- Target See all CD41, CD61 Antibodies
- CD41, CD61 (CD41,CD61)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD41, CD61 antibody is conjugated to PerCP
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Application
- Flow Cytometry (FACS)
- Purpose
- Anti-Hu CD41/CD61 (PAC-1 epitope) PerCP
- Specificity
- The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
- Purification
- Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Human platelets
- Clone
- PAC-1
- Isotype
- IgM kappa
- Top Product
- Discover our top product CD41, CD61 Primary Antibody
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anti-CD41,CD61 antibody
Reactivity: Human, Cow FACS, IP, ELISA, ICC Host: Mouse Monoclonal IVA30 unconjugated
anti-CD41,CD61 antibodyReactivity: Human FACS, IP, ICC Host: Mouse Monoclonal PAC-1 unconjugated
anti-CD41,CD61 antibody (PE)Reactivity: Human FACS Host: Mouse Monoclonal PAC-1 PE
anti-CD41,CD61 antibody (FITC)Reactivity: Human FACS Host: Mouse Monoclonal PAC-1 FITC
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- Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- CD41, CD61 (CD41,CD61)
- Alternative Name
- CD41/CD61 (CD41, CD61 Products)
- Background
- CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa
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