FCRL4 antibody (PE)

Catalog No. ABIN7505907

Product Details anti-FCRL4 Antibody (PE)

Target: FCRL4 (Fc Receptor-Like 4 (FCRL4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCRL4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu CD307d PE

Specificity: The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: DNA-immunization followed by a boost with CD307d-transfected cells

Clone: A1

Isotype: IgG2a kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for FCRL4

Target: FCRL4 (Fc Receptor-Like 4 (FCRL4))

Alternative Name: CD307d (FCRL4 Products)

Synonyms: CD307d antibody, FCRH4 antibody, IGFP2 antibody, IRTA1 antibody, FCRL4 antibody, Fc receptor like 4 antibody, Fc receptor-like 4 antibody, Fc receptor-like 4 L homeolog antibody, FCRL4 antibody, fcrl4 antibody, fcrl4.L antibody

Background: Fc receptor like 4,CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG). Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.,FcRL4, FCRH4, IRTA1

Gene ID: 83417

UniProt: Q96PJ5