The mouse monoclonal antibody E3 recognizes an extracellular epitope of CD307a, a transmembrane glycoprotein expressed predominantly on the surface of mature B cells.
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogen
DNA-immunization followed by a boost with the CD307a transfected cells
FCRL1
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 488
Application Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
CD307a antibody, FCRH1 antibody, IFGP1 antibody, IRTA5 antibody, A230020G22Rik antibody, Bxmas1 antibody, Bxmh1 antibody, Bxmh1b antibody, Fcrh1 antibody, Fcrh1l antibody, Fcrh1s antibody, Ifgp1 antibody, FCRL1 antibody, MGC148384 antibody, Fc receptor like 1 antibody, Fc receptor-like 1 antibody, Fc receptor-like protein 1 antibody, FCRL1 antibody, Fcrl1 antibody, LOC612035 antibody
Background
Fc receptor like 1,CD307a is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITAM motifs in its cytoplasmic domain. CD307a is expressed mainly on the surface of mature B-cells, and is down-regulated in germinal center B-cells. Expression of CD307a is higher in patients with autoimmune diseases, compared with healthy controls.,FcRL1, FcRH1, IRTA5