FCRL1 antibody (PE)

Catalog No. ABIN7505901

Product Details anti-FCRL1 Antibody (PE)

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCRL1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu CD307a PE

Specificity: The mouse monoclonal antibody E3 recognizes an extracellular epitope of CD307a, a transmembrane glycoprotein expressed predominantly on the surface of mature B cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: DNA-immunization followed by a boost with the CD307a transfected cells

Clone: E3

Isotype: IgG1 kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for FCRL1

Target: FCRL1 (Fc Receptor-Like 1 (FCRL1))

Alternative Name: CD307a (FCRL1 Products)

Background: Fc receptor like 1,CD307a is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITAM motifs in its cytoplasmic domain. CD307a is expressed mainly on the surface of mature B-cells, and is down-regulated in germinal center B-cells. Expression of CD307a is higher in patients with autoimmune diseases, compared with healthy controls.,FcRL1, FcRH1, IRTA5

Gene ID: 115350

UniProt: Q96LA6