BTLA antibody (PE)
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- Target See all BTLA Antibodies
- BTLA (B and T Lymphocyte Associated (BTLA))
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Reactivity
- Human, Non-Human Primate
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BTLA antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Purpose
- Anti-Hu CD272 PE
- Specificity
- The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- cells transfected with human CD272
- Clone
- MIH26
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product BTLA Primary Antibody
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anti-B and T Lymphocyte Associated (BTLA) antibody
BTLA Reactivity: Human WB, FACS Host: Mouse Monoclonal 2E4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 179-289) antibodyBTLA Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 4B12A7 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 5G1G10 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 221-289) antibodyBTLA Reactivity: Human, Mouse WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human WB, FACS, IF Host: Mouse Monoclonal 2G2 unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4D6 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 101-150) antibodyBTLA Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal MIH26 unconjugated
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- Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Alternative Name
- CD272 (BTLA Products)
- Synonyms
- BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
- Background
- B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
- Gene ID
- 151888
- UniProt
- Q7Z6A9
- Pathways
- Cancer Immune Checkpoints
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