SIRPG antibody (PE)

Catalog No. ABIN7505871

Product Details anti-SIRPG Antibody (PE)

Target: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPG antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu CD172g PE

Specificity: The mouse monoclonal antibody OX-119 recognizes an extracellular epitope on CD172g, an approximately 55 kDa transmembrane glycoprotein expressed on most T cells, as well as on NK cells and some B cell populations.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant human CD172g

Clone: OX-119

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for SIRPG

Target: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Alternative Name: CD172g (SIRPG Products)

Synonyms: CD172g antibody, SIRP-B2 antibody, SIRPB2 antibody, SIRPgamma antibody, bA77C3.1 antibody, SIRPG antibody, signal regulatory protein gamma antibody, signal-regulatory protein gamma antibody, SIRPG antibody, LOC716034 antibody, LOC102138723 antibody

Background: Signal regulatory protein gamma,CD172g is a transmembrane glycoprotein, which may play a role in inter-T cellular signaling by binding CD47, and thus in influencing T cell behaviour. CD172g is expressed on mature thymocytes, CD4+ T cells, CD8+ T cells, NK cells, and some B cells. It is absent on myeloid cells. Engagement of CD172g by CD47 expressed on antigen presenting cells results in enhanced antigen-specific T cell proliferation and costimulates T cell activation.,SIRP gamma, SIRP-B2

Gene ID: 55423

UniProt: Q9P1W8