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ADAM10 antibody

ADAM10 Reactivity: Human WB, FACS, IP, IHC (p), IHC (fro) Host: Mouse Monoclonal 11G2 unconjugated
Catalog No. ABIN7505861
  • Target See all ADAM10 Antibodies
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Reactivity
    • 66
    • 29
    • 29
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 11
    • 2
    • 1
    Mouse
    Clonality
    • 48
    • 21
    Monoclonal
    Conjugate
    • 30
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM10 antibody is un-conjugated
    Application
    • 42
    • 14
    • 14
    • 14
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purpose
    Anti-Hu CD156c Purified
    Specificity
    The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.
    No Cross-Reactivity
    Mouse
    Purification
    Purified by protein-A affinity chromatography.
    Immunogen
    Jurkat cells
    Clone
    11G2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ADAM10 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-5 μg/mL, extracellular and intracellular staining.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Alternative Name
    CD156c (ADAM10 Products)
    Background
    ADAM metallopeptidase domain 10,CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.,ADAM10, AD10, RAK, MADM, HsT18717
    Gene ID
    102
    UniProt
    O14672
    Pathways
    Notch Signaling, EGFR Signaling Pathway
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