MORG1 antibody (AA 201-315) (Biotin)
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- Target See all MORG1 (wdr83) Antibodies
- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
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Binding Specificity
- AA 201-315
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Reactivity
- Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MORG1 antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MAPK organizer 1
- Isotype
- IgG
- Top Product
- Discover our top product wdr83 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
- Alternative Name
- MAPK organizer 1 (wdr83 Products)
- Synonyms
- MORG1 antibody, 1500041N16Rik antibody, Morg1 antibody, RGD1306947 antibody, morg1 antibody, MAPK organizer 1 antibody, wu:fj29g04 antibody, zgc:92654 antibody, WD repeat domain 83 antibody, WD repeat domain containing 83 antibody, WD repeat domain 83 L homeolog antibody, WDR83 antibody, Wdr83 antibody, wdr83.L antibody, wdr83 antibody
- Background
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Synonyms: MORG1, WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83
Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
- Gene ID
- 84292
- UniProt
- Q9BRX9
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