UGDH antibody (AA 421-494)

Catalog No. ABIN720370

Product Details anti-UGDH Antibody

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Binding Specificity: AA 421-494

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGDH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UGDH/UDPGDH

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Alternative Name: UGDH (UGDH Products)

Synonyms: 8310 antibody, BG01214 antibody, CG10072 antibody, Dmel\\CG10072 antibody, Sgl antibody, UDP-GlcDH antibody, UDPGDH antibody, XIII antibody, kiwi antibody, l(3)05007 antibody, l(3)08310 antibody, l(3)10503 antibody, l(3)65CEd antibody, l(3)SG9 antibody, ska antibody, sl antibody, ik:tdsubc_2a8 antibody, tdsubc_2a8 antibody, xx:tdsubc_2a8 antibody, gdh antibody, ugd antibody, ugdh antibody, ugdhb antibody, xugdh antibody, udpgdh antibody, udpg antibody, ugdha antibody, BA5434 antibody, SCBAC19G2.07 antibody, AGR_L_1413 antibody, udg antibody, GDH antibody, UGD antibody, Udpgdh antibody, sugarless antibody, UDP-glucose 6-dehydrogenase antibody, UDP-glucose 6-dehydrogenase L homeolog antibody, UDP-glucose 6-dehydrogenase S homeolog antibody, UDP-glucose dehydrogenase WcvB antibody, UDP-glucose dehydrogenase antibody, sgl antibody, ugdh antibody, ugdh.L antibody, UGDH antibody, ugdh.S antibody, hasB antibody, ugdH antibody, ugd antibody, SCO3052 antibody, wcvB antibody, CNL06460 antibody, Ugdh antibody

Background:

Synonyms: UDP glucose dehydrogenase, GDH, UDP Glc dehydrogenasev UDP GlcDH, UDP glucose 6 dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGD, Ugdh, UGDH_HUMAN, Uridine diphospho glucose dehydrogenase.

Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].

Gene ID: 7358

Pathways: Glycosaminoglycan Metabolic Process