Recombinant ITGA4 (Natalizumab Biosimilar) antibody
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- Target See all ITGA4 (Natalizumab Biosimilar) products
- ITGA4 (Natalizumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
- Mouse
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Clonality
- Chimeric
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Conjugate
- This ITGA4 (Natalizumab Biosimilar) antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Blocking Reagent (BR)
- Purpose
- Anti-Integrin alpha 4 [Natalizumab], Mouse IgG1, kappa
- Specificity
- This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
- Characteristics
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Original Species of Ab: Human
Original Format of Ab: IgG4
- Purification
- Protein A affinity purified
- Immunogen
- The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
- Isotype
- IgG1 kappa
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anti-ITGA4 (Natalizumab Biosimilar) antibody
Research Grade Reactivity: Human FACS Host: Humanized Monoclonal unconjugated Recombinant Antibody
anti-ITGA4 (Natalizumab Biosimilar) antibodyReactivity: Human FACS, BR Host: Rabbit Chimeric unconjugated Recombinant Antibody
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- Application Notes
- This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
- Comment
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This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- ITGA4 (Natalizumab Biosimilar)
- Abstract
- ITGA4 (Natalizumab Biosimilar) Products
- Background
- CD49D, alpha 4 subunit of VLA-4 receptor, ITGA4, Integrin alpha-IV
- UniProt
- P13612
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