Recombinant Trastuzumab antibody
Reactivity: Human
Host: Mouse
Monoclonal
AY1b
unconjugated
Recombinant Antibody
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- Target See all Trastuzumab products
- Trastuzumab
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Purpose
- Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD)
- Characteristics
- Anti-idiotypic Antibodies
- Immunogen
- Anti-Trastuzumab Antibody (AY1b) are expressed from human 293 cells (HEK293).
- Clone
- AY1b
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Storage
- -20 °C
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- Target
- Trastuzumab
- Abstract
- Trastuzumab Products
- Background
- Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.
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