Recombinant Bevacizumab antibody
MALS verified
Reactivity: Human
Host: Mouse
Monoclonal
AY10
unconjugated
Recombinant Antibody
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- Target See all Bevacizumab products
- Bevacizumab
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Bevacizumab antibody is un-conjugated
- Purpose
- Anti-Bevacizumab Antibody (AY10) (MALS verified, recommended for PK/PD)
- Characteristics
- Anti-idiotypic Antibodies
- Grade
- MALS verified
- Immunogen
- Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.
- Clone
- AY10
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Storage
- -20 °C
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- Target
- Bevacizumab
- Abstract
- Bevacizumab Products
- Target Type
- Antibody
- Background
- A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.
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