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Recombinant Bevacizumab antibody (Biotin)

Reactivity: Human Host: Mouse Monoclonal AY13 Biotin Recombinant Antibody
Catalog No. ABIN7488554
  • Target See all Bevacizumab products
    Bevacizumab
    Antibody Type
    Recombinant Antibody
    Reactivity
    Human
    Host
    • 1
    Mouse
    Clonality
    • 1
    Monoclonal
    Conjugate
    • 1
    This Bevacizumab antibody is conjugated to Biotin
    Purpose
    Biotinylated Anti-Bevacizumab Antibody (AY13) (recommended for PK/PD)
    Characteristics
    Anti-idiotypic Antibodies
    Immunogen
    Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.
    Clone
    AY13
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Storage
    -20 °C
  • Target
    Bevacizumab
    Abstract
    Bevacizumab Products
    Target Type
    Antibody
    Background
    A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.
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