Recombinant Androgen Receptor antibody (AA 1-100)

Catalog No. ABIN7477375

Product Details anti-Androgen Receptor Antibody

Target: Androgen Receptor (AR)

Antibody Type: Recombinant Antibody

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Androgen Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Synthetic peptide corresponding to residues (within aa1-100) of Androgen Receptor.

Clone: MSVA-367R

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Comment:

Positive Control: Kidney: An at least weak to moderate nuclear AR immunostaining should be seen in a subset of kidney tubuli and of glomerular cells.

Negative Control: Colon: AR immunostaining should be absent in colonic mucosa.

Protocol: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non- hazardous.

Target Details for Androgen Receptor

Target: Androgen Receptor (AR)

Alternative Name: Androgen Receptor (AR Products)

Synonyms: AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody

Background: AIS, Dihydrotestosterone receptor (DHTR), HUMARA, HYSP1, Kennedy disease (KD), Nuclear receptor subfamily 3 group C member 4 (NR3C4), SMAX1, Spinal and bulbar muscular atrophy (SBMA), Testicular Feminization (TFM),Androgen Receptor antibody validated for immunohistochemistry on 76 different Normal Tissues

UniProt: P10275

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding