CD44 Standard antibody (PE-Cy7)

Catalog No. ABIN7470037

Product Details anti-CD44 Standard Antibody (PE-Cy7)

Target: CD44 Standard (CD44s)

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 Standard antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: OX-49

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Matching Isotype Control: PE/Cyanine7 Mouse IgG2a, κ Isotype Control (ABIN7469791)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD44 Standard

Target: CD44 Standard (CD44s)

Alternative Name: CD44H (CD44s Products)

Background: Pgp-1, H-CAM, CD44s,CD44H,CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Gene ID: 12505

UniProt: P26051