CD45RO antibody (FITC)
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- Target See all CD45RO products
- CD45RO
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD45RO antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Clone
- UCHL1
- Isotype
- IgG2a, kappa
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Matching Isotype Control: FITC Mouse IgG2a, κ Isotype Control (ABIN7469777)
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Target
- CD45RO
- Alternative Name
- CD45RO (CD45RO Products)
- Background
- CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
- Gene ID
- 5788
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