SUS1 antibody

Catalog No. ABIN7469076

Product Details anti-SUS1 Antibody

Target: SUS1 (ENY2) (Transcription and mRNA Export Factor ENY2 (ENY2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ENY2. The exact sequence is proprietary.

Clone: GT245

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SUS1

Target: SUS1 (ENY2) (Transcription and mRNA Export Factor ENY2 (ENY2))

Alternative Name: ENY2 transcription and export complex 2 subunit (ENY2 Products)

Synonyms: e(y)2 antibody, ENY2, transcription and export complex 2 subunit antibody, ENY2 antibody

Background:

Synonyms: ENY2 transcription and export complex 2 subunit , DC6 , Sus1 , e(y)2

Background: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Molecular Weight: 12 kDa

Gene ID: 56943

UniProt: Q9NPA8