SUS1 antibody
ENY2
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
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- Target See all SUS1 (ENY2) products
- SUS1 (ENY2) (Transcription and mRNA Export Factor ENY2 (ENY2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SUS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Cross-Reactivity
- Human
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ENY2. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.62 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- SUS1 (ENY2) (Transcription and mRNA Export Factor ENY2 (ENY2))
- Alternative Name
- ENY2 transcription and export complex 2 subunit (ENY2 Products)
- Synonyms
- e(y)2 antibody, ENY2, transcription and export complex 2 subunit antibody, ENY2 antibody
- Background
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Synonyms: ENY2 transcription and export complex 2 subunit , DC6 , Sus1 , e(y)2
Background: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
- Molecular Weight
- 12 kDa
- Gene ID
- 56943
- UniProt
- Q9NPA8
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