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TNNT1 antibody

TNNT1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7468979
  • Target See all TNNT1 Antibodies
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    Reactivity
    • 25
    • 14
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 24
    • 4
    • 1
    Rabbit
    Clonality
    • 27
    • 2
    Polyclonal
    Conjugate
    • 17
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNT1 antibody is un-conjugated
    Application
    • 22
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Pig
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Full length human Troponin T1 (slow) skeletal muscle Recombinant protein.
    Isotype
    IgG
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    Discover our top product TNNT1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: H1299

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.89 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    TNNT1 (Slow Skeletal Troponin T (TNNT1))
    Alternative Name
    troponin T1, slow skeletal type (TNNT1 Products)
    Synonyms
    ANM antibody, NEM5 antibody, STNT antibody, TNT antibody, TNTS antibody, TNNI1 antibody, AW146156 antibody, Tnt antibody, sTnT antibody, ssTnT antibody, Fang2 antibody, tnTs antibody, Tnnt antibody, zgc:193831 antibody, zgc:193865 antibody, troponin T1, slow skeletal type antibody, troponin I1, slow skeletal type antibody, troponin T1, skeletal, slow antibody, troponin T1, slow skeletal type S homeolog antibody, troponin T type 1 (skeletal, slow) antibody, TNNT1 antibody, TNNI1 antibody, Tnnt1 antibody, tnnt1.S antibody, tnnt1 antibody
    Background

    Synonyms: troponin T1, slow skeletal type , ANM , NEM5 , STNT , TNT , TNTS

    Background: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    Molecular Weight
    33 kDa
    Gene ID
    7138
    UniProt
    P13805
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