Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Serrate RNA Effector Molecule antibody (N-Term)

SE Reactivity: Human WB, IHC (p), IP, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7468958
  • Target See all Serrate RNA Effector Molecule (SE) products
    Serrate RNA Effector Molecule (SE)
    Binding Specificity
    N-Term
    Reactivity
    Human
    Host
    • 1
    • 1
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    This Serrate RNA Effector Molecule antibody is un-conjugated
    Application
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human ARS2. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T , A431 , HeLa , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.76 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Serrate RNA Effector Molecule (SE)
    Alternative Name
    serrate, RNA effector molecule (SE Products)
    Synonyms
    ARS2 antibody, ASR2 antibody, serrate antibody, SERRATE antibody, T20P8.15 antibody, T20P8_15 antibody, serrate, RNA effector molecule antibody, C2H2 zinc-finger protein SERRATE (SE) antibody, SRRT antibody, SE antibody
    Background

    Synonyms: serrate, RNA effector molecule , ARS2 , ASR2 , serrate

    Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.

    Molecular Weight
    101 kDa
    Gene ID
    51593
    UniProt
    Q9BXP5
You are here:
Support