RXFP1 antibody (C-Term)

Catalog No. ABIN7468871

Product Details anti-RXFP1 Antibody

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RXFP1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LGR7. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RXFP1

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Alternative Name: relaxin family peptide receptor 1 (RXFP1 Products)

Synonyms: LGR7 antibody, RXFPR1 antibody, Gm1018 antibody, Lgr7 antibody, RXFP2 antibody, relaxin/insulin like family peptide receptor 1 antibody, relaxin/insulin-like family peptide receptor 1 antibody, RXFP1 antibody, rxfp1 antibody, Rxfp1 antibody

Background:

Synonyms: relaxin family peptide receptor 1 , LGR7 , RXFPR1

Background: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Molecular Weight: 87 kDa

Gene ID: 59350

UniProt: Q9HBX9

Pathways: Myometrial Relaxation and Contraction