PSMB7 antibody
-
- Target See all PSMB7 Antibodies
- PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PSMB7 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Proteasome 20S beta 7. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product PSMB7 Primary Antibody
-
-
- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
-
Positive Control: Mouse brain , HepG2
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- PSMB7 (Proteasome (Prosome, Macropain) Subunit, beta Type, 7 (PSMB7))
- Alternative Name
- proteasome subunit beta 7 (PSMB7 Products)
- Synonyms
- DDBDRAFT_0185624 antibody, DDBDRAFT_0232933 antibody, DDB_0185624 antibody, DDB_0232933 antibody, AU020723 antibody, MC14 antibody, Z antibody, 20S proteasome subunit beta-7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 S homeolog antibody, proteasome subunit beta 7 antibody, proteasome (prosome, macropain) subunit, beta type, 7 antibody, proteasome (prosome, macropain) subunit, beta type 7 antibody, psmB7 antibody, psmb7.S antibody, PSMB7 antibody, Psmb7 antibody
- Background
-
Synonyms: proteasome subunit beta 7 , Z
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq]
- Molecular Weight
- 30 kDa
- Gene ID
- 5695
- UniProt
- Q99436
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
-