POLR2C antibody

Catalog No. ABIN7468764

Product Details anti-POLR2C Antibody

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human POLR2C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.98 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for POLR2C

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Alternative Name: RNA polymerase II subunit C (POLR2C Products)

Synonyms: RPB3 antibody, RPB31 antibody, hRPB33 antibody, hsRPB3 antibody, 33kDa antibody, Rpo2-3 antibody, mRBP31 antibody, zgc:56285 antibody, wu:fk48d01 antibody, MGC76329 antibody, MGC81245 antibody, POLR2C antibody, polr2c antibody, rpb3 antibody, RNA polymerase II subunit C antibody, polymerase (RNA) II (DNA directed) polypeptide C antibody, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa antibody, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa S homeolog antibody, POLR2C antibody, Polr2c antibody, polr2c antibody, polr2c.S antibody

Background:

Synonyms: RNA polymerase II subunit C , RPB3 , RPB31 , hRPB33 , hsRPB3

Background: This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq]

Molecular Weight: 31 kDa

Gene ID: 5432

UniProt: P19387

Pathways: Regulatory RNA Pathways