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POLE3 antibody

KO Validated POLE3 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7468761
  • Target See all POLE3 Antibodies
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Reactivity
    • 39
    • 20
    • 16
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 6
    Rabbit
    Clonality
    • 36
    • 3
    Polyclonal
    Conjugate
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This POLE3 antibody is un-conjugated
    Application
    • 22
    • 9
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse
    Purification
    Purified by antigen-affinity chromatography.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human DNA polymerase epsilon 3. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product POLE3 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.01 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Alternative Name
    DNA polymerase epsilon 3, accessory subunit (POLE3 Products)
    Synonyms
    NCU04548.1 antibody, GB14966 antibody, zgc:73351 antibody, 1810034K18Rik antibody, YBL1 antibody, CHARAC17 antibody, CHRAC17 antibody, p17 antibody, DNA polymerase epsilon 3, accessory subunit antibody, polymerase (DNA directed), epsilon 3, accessory subunit antibody, DNA polymerase epsilon antibody, DNA polymerase epsilon p17 subunit antibody, DNA polymerase epsilon subunit 3 antibody, polymerase (DNA directed), epsilon 3 (p17 subunit) antibody, POLE3 antibody, pole3 antibody, NCU04548 antibody, CpipJ_CPIJ008666 antibody, Bm1_04865 antibody, Bm1_07285 antibody, CTRG_00708 antibody, LOAG_09571 antibody, LOC726923 antibody, Pole3 antibody
    Background

    Synonyms: DNA polymerase epsilon 3, accessory subunit , CHARAC17 , CHRAC17 , CHRAC2 , YBL1 , p17

    Background: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM]

    Molecular Weight
    17 kDa
    Gene ID
    54107
    UniProt
    Q9NRF9
    Pathways
    DNA Damage Repair
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