Histone H1.1 antibody

Catalog No. ABIN7468457

Product Details anti-Histone H1.1 Antibody

Target: Histone H1.1 (HIST1H1A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H1.1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Histone H1.1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa nuclear extract Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.29 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Histone H1.1

Target: Histone H1.1 (HIST1H1A)

Alternative Name: histone cluster 1 H1 family member a (HIST1H1A Products)

Synonyms: H1.1 antibody, H1a antibody, H1f1 antibody, H1var3 antibody, H1A antibody, H1F1 antibody, HIST1 antibody, histone cluster 1, H1a antibody, histone cluster 1 H1 family member a antibody, HIST1H1A antibody, Hist1h1a antibody

Background:

Synonyms: histone cluster 1 H1 family member a , H1.1 , H1A , H1F1 , HIST1

Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq]

Molecular Weight: 22 kDa

Gene ID: 3024

UniProt: Q02539