GATM antibody
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- Target See all GATM products
- GATM (Glycine Amidinotransferase (GATM))
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GATM antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Zebrafish (Danio rerio)
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human GATM. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Glycine Amidinotransferase (GATM) (N-Term) antibody
GATM Reactivity: Human WB, EIA, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: mouse liver
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- GATM (Glycine Amidinotransferase (GATM))
- Alternative Name
- glycine amidinotransferase (GATM Products)
- Synonyms
- AGAT antibody, AT antibody, CCDS3 antibody, glycine amidinotransferase antibody, Glycine amidinotransferase antibody, BRAFLDRAFT_280917 antibody, Bmur_0416 antibody, GATM antibody
- Background
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Synonyms: glycine amidinotransferase , AGAT , AT , CCDS3
Background: This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq]
- Molecular Weight
- 48 kDa
- Gene ID
- 2628
- UniProt
- P50440
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