FZD6 antibody

Catalog No. ABIN7468346

Product Details anti-FZD6 Antibody

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD6 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Frizzled 6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FZD6

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Alternative Name: frizzled class receptor 6 (FZD6 Products)

Synonyms: zgc:65879 antibody, zgc:77440 antibody, fz6 antibody, frz6 antibody, Xfrz6 antibody, frizzled6 antibody, frizzled-6 antibody, FZ-6 antibody, FZ6 antibody, HFZ6 antibody, NDNC10 antibody, Frizzled-6 antibody, Fz6 antibody, frizzled class receptor 6 antibody, frizzled class receptor 6 S homeolog antibody, fzd6 antibody, fzd6.S antibody, FZD6 antibody, Fzd6 antibody

Background:

Synonyms: frizzled class receptor 6 , FZ-6 , FZ6 , HFZ6 , NDNC10

Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other Fz family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif. [provided by RefSeq]

Molecular Weight: 79 kDa

Gene ID: 8323

UniProt: O60353

Pathways: WNT Signaling, Tube Formation