HLA-DOA antibody

Catalog No. ABIN7467728

Product Details anti-HLA-DOA Antibody

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DOA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human HLA-DOA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.64 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HLA-DOA

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Alternative Name: major histocompatibility complex, class II, DO alpha (HLA-DOA Products)

Synonyms: HLA-DNA antibody, HLA-DZA antibody, HLADZ antibody, major histocompatibility complex, class II, DO alpha antibody, HLA-DOA antibody

Background: Major histocompatibility complex, class II, DO alpha , HLA-DNA , HLA-DZA , HLADZ,HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]

Molecular Weight: 28 kDa

Gene ID: 3111

UniProt: P06340

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response