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ITM2B antibody

ITM2B Reactivity: Human WB, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7467380
  • Target See all ITM2B Antibodies
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    Reactivity
    • 26
    • 16
    • 2
    • 1
    Human
    Host
    • 31
    • 4
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 36
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITM2B antibody is un-conjugated
    Application
    • 26
    • 21
    • 20
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ITM2B. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ITM2B Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: rat brain , RT-4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.81 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    Alternative Name
    integral membrane protein 2B (ITM2B Products)
    Synonyms
    ABRI antibody, BRI antibody, BRI2 antibody, BRICD2B antibody, E25B antibody, E3-16 antibody, FBD antibody, imBRI2 antibody, AI256040 antibody, Bri antibody, Bri2 antibody, Bricd2b antibody, D14Sel6 antibody, E25BMM antibody, itm2b antibody, zgc:55770 antibody, zgc:85688 antibody, wu:fc05f02 antibody, MGC52745 antibody, MGC76131 antibody, ITM2B antibody, itm2bl antibody, wu:fb94b03 antibody, zgc:64142 antibody, integral membrane protein 2B antibody, integral membrane protein 2Ba antibody, integral membrane protein 2B L homeolog antibody, integral membrane protein 2b antibody, integral membrane protein 2Bb antibody, ITM2B antibody, Itm2b antibody, itm2ba antibody, itm2b.L antibody, itm2b antibody, itm2bb antibody
    Background
    Integral membrane protein 2B , ABRI , BRI , BRI2 , BRICD2B , E25B , E3-16 , FBD , RDGCA , imBRI2,Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq]
    Molecular Weight
    30 kDa
    Gene ID
    9445
    UniProt
    Q9Y287
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