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IMPA1 antibody

IMPA1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7467238
  • Target See all IMPA1 Antibodies
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    Reactivity
    • 32
    • 14
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 3
    Rabbit
    Clonality
    • 30
    • 2
    Polyclonal
    Conjugate
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This IMPA1 antibody is un-conjugated
    Application
    • 12
    • 7
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Full length human IMPA1 Recombinant protein.
    Isotype
    IgG
    Top Product
    Discover our top product IMPA1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: PC-3 , SK-N-SH

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    Alternative Name
    inositol monophosphatase 1 (IMPA1 Products)
    Synonyms
    zgc:100926 antibody, 2610002K09Rik antibody, 2900059K10Rik antibody, AI325909 antibody, IMP antibody, IMPA antibody, impa antibody, inositol monophosphatase 1 antibody, inositol(myo)-1(or 4)-monophosphatase 1 antibody, inositol (myo)-1(or 4)-monophosphatase 1 antibody, inositol monophosphatase antibody, inositol(myo)-1(or 4)-monophosphatase 1 S homeolog antibody, impa1 antibody, Impa1 antibody, IMPA1 antibody, impa1.S antibody
    Background
    Inositol monophosphatase 1 , IMP , IMPA , MRT59,This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq]
    Molecular Weight
    30 kDa
    Gene ID
    3612
    UniProt
    P29218
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