HIST1H2AE antibody

Catalog No. ABIN7467182

Product Details anti-HIST1H2AE Antibody

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2AE antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human Histone H2A Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Alternative Name: histone cluster 1, H2ae (HIST1H2AE Products)

Synonyms: H2A.1 antibody, H2A.2 antibody, H2A/a antibody, H2AFA antibody, histone cluster 1 H2A family member e antibody, HIST1H2AE antibody

Background: H2A.1 Antibody , histone cluster 1, H2ae Antibody , HIST1H2AE Antibody , H2AFA Antibody , H2A.2 Antibody , H2A/a Antibody,Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]

Molecular Weight: 14 kDa

Gene ID: 3012

Pathways: Telomere Maintenance