HBG2 antibody

Catalog No. ABIN7467138

Product Details anti-HBG2 Antibody

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human Hemoglobin gamma G Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.71 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HBG2

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Alternative Name: hemoglobin subunit gamma 2 (HBG2 Products)

Synonyms: TNCY antibody, hbb2 antibody, MGC88976 antibody, HBG antibody, hemoglobin subunit gamma 2 antibody, hemoglobin subunit gamma 2 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma 2 S homeolog antibody, HBG2 antibody, hbg2 antibody, hbg2.L antibody, hbg2.S antibody

Background: Hemoglobin subunit gamma 2 , HBG-T1 , TNCY,The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq]

Molecular Weight: 16 kDa

Gene ID: 3048

UniProt: P69892