QTRT1 antibody (Catalytic Subunit 1)

Catalog No. ABIN7467096

Product Details anti-QTRT1 Antibody

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Binding Specificity: Catalytic Subunit 1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QTRT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human QTRT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1 , PC-3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.89 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for QTRT1

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Alternative Name: queuine tRNA-ribosyltransferase (QTRT1 Products)

Synonyms: CG4947 antibody, Dmel\\CG4947 antibody, TGT antibody, tgt antibody, zgc:66378 antibody, FP3235 antibody, TGUT antibody, 2610028E17Rik antibody, Tgt antibody, Tgut antibody, tRNA-guanine transglycosylase antibody, queuine tRNA-ribosyltransferase 1 S homeolog antibody, queuine tRNA-ribosyltransferase 1 antibody, queuine tRNA-ribosyltransferase catalytic subunit 1 antibody, Tgt antibody, Olsu_0732 antibody, Palpr_1298 antibody, Riean_1227 antibody, Calni_1240 antibody, Ftrac_0312 antibody, Ocepr_1541 antibody, Sulku_0977 antibody, Tmar_0854 antibody, Bache_2323 antibody, Nitsa_1291 antibody, Isop_1657 antibody, Despr_0021 antibody, Pedsa_1842 antibody, Corgl_1148 antibody, Mahau_0921 antibody, Theth_0831 antibody, qtrt1.S antibody, qtrt1 antibody, QTRT1 antibody, Qtrt1 antibody

Background: Queuine tRNA-ribosyltransferase catalytic subunit 1 , FP3235 , TGT , TGUT,tRNA-guanine transglycosylase (TGT, EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14, MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]).[supplied by OMIM]

Molecular Weight: 44 kDa

Gene ID: 81890

UniProt: Q9BXR0

Pathways: Ribonucleoside Biosynthetic Process