STK36 antibody (N-Term)

Catalog No. ABIN7466792

Product Details anti-STK36 Antibody

Target: STK36 (serine/threonine Kinase 36 (STK36))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK36 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human STK36. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for STK36

Target: STK36 (serine/threonine Kinase 36 (STK36))

Alternative Name: serine/threonine kinase 36 (STK36 Products)

Synonyms: FU antibody, fused-like antibody, 1700112N14Rik antibody, B930045J24 antibody, Fused antibody, mKIAA1278 antibody, fu antibody, si:dkey-180i4.3 antibody, zgc:152944 antibody, serine/threonine kinase 36 antibody, serine/threonine kinase 36 (fused homolog, Drosophila) antibody, STK36 antibody, Stk36 antibody, stk36 antibody

Background: Serine/threonine kinase 36 , FU,Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.

Molecular Weight: 144 kDa

Gene ID: 27148

UniProt: Q9NRP7