RNF181 antibody

Catalog No. ABIN7466417

Product Details anti-RNF181 Antibody

Target: RNF181 (Ring Finger Protein 181 (RNF181))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF181 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RNF181. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RNF181

Target: RNF181 (Ring Finger Protein 181 (RNF181))

Alternative Name: ring finger protein 181 (RNF181 Products)

Synonyms: 1700047F16Rik antibody, 2500002L14Rik antibody, 6230415N01Rik antibody, C77350 antibody, zgc:56424 antibody, ring finger protein 181 antibody, ring finger protein 181 S homeolog antibody, RNF181 antibody, Rnf181 antibody, rnf181.S antibody, rnf181 antibody

Background: Ring finger protein 181 , HSPC238,RNF181 binds the integrin alpha-IIb (ITGA2B, MIM 607759)/beta-3 (ITGB3, MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM]

Molecular Weight: 18 kDa

Gene ID: 51255

UniProt: Q9P0P0