PHOX2B antibody (N-Term)

Catalog No. ABIN7466363

Product Details anti-PHOX2B Antibody

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PHOX2B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32 , SK-N-AS , SH-SY5Y

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.42 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: paired like homeobox 2B (PHOX2B Products)

Synonyms: phox2 antibody, xphox2b antibody, phox2b antibody, PHOX2B antibody, pmx2b antibody, nbphox antibody, NBLST2 antibody, NBPhox antibody, PMX2B antibody, Dilp1 antibody, Pmx2b antibody, paired-like homeobox 2b antibody, paired like homeobox 2b S homeolog antibody, paired-like homeobox 2bb antibody, paired like homeobox 2b antibody, phox2b antibody, phox2b.S antibody, phox2bb antibody, PHOX2B antibody, Phox2b antibody

Background: Paired like homeobox 2B , CCHS , NBLST2 , NBPhox , PMX2B,The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq]

Molecular Weight: 32 kDa

Gene ID: 8929

UniProt: Q99453