MAP4K6 antibody (C-Term)

Catalog No. ABIN7466034

Product Details anti-MAP4K6 Antibody

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human MAP4K6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MAP4K6

Target: MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))

Alternative Name: misshapen like kinase 1 (MINK1 Products)

Synonyms: MINK1 antibody, MINK antibody, B55 antibody, MAP4K6 antibody, YSK2 antibody, ZC3 antibody, hMINK antibody, hMINKbeta antibody, MEKKK 6 antibody, Map4k6 antibody, RP23-122P1.6 antibody, Ysk2 antibody, misshapen like kinase 1 antibody, misshapen-like kinase 1 antibody, misshapen-like kinase 1 (zebrafish) antibody, MINK1 antibody, Mink1 antibody

Background: Misshapen like kinase 1 , B55 , MAP4K6 , MINK , YSK2 , ZC3,This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]

Molecular Weight: 150 kDa

Gene ID: 50488

UniProt: Q8N4C8

Pathways: Synaptic Membrane