NYS48/HAUS8 antibody (pSer19, pSer20)

Catalog No. ABIN7465974

Product Details anti-NYS48/HAUS8 Antibody

Target: NYS48/HAUS8 (HAUS8) (HAUS Augmin-Like Complex, Subunit 8 (HAUS8))

Binding Specificity: pSer19, pSer20

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NYS48/HAUS8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Affinity purified using antigen

Immunogen: Synthetic phosphopeptide corresponding to the amino acids around Ser 19/20 conjugated to KLH

Isotype: IgG

Application Details

Application Notes: Recommended Starting Dilutions:
For WB: Use at a dilution of 1:100
For ICC/IF: Use at a dilution of 1:50
Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.

Comment:

Positive Control: HeLa , K562 , Blocking peptide (GTX70011-PEP)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 1X PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NYS48/HAUS8

Target: NYS48/HAUS8 (HAUS8) (HAUS Augmin-Like Complex, Subunit 8 (HAUS8))

Alternative Name: HAUS augmin like complex subunit 8 (HAUS8 Products)

Synonyms: 2410004L22Rik antibody, Hice1 antibody, NY-SAR-48 antibody, hice1 antibody, DGT4 antibody, HICE1 antibody, Ny-sar-48 antibody, RGD1311565 antibody, 4HAUS augmin-like complex, subunit 8 antibody, HAUS augmin like complex subunit 8 L homeolog antibody, HAUS augmin like complex subunit 8 antibody, HAUS augmin-like complex, subunit 8 antibody, Haus8 antibody, haus8.L antibody, HAUS8 antibody

Background: HAUS augmin like complex subunit 8 , DGT4 , HICE1 , NY-SAR-48,HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220], Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

Molecular Weight: 45 kDa

Gene ID: 93323

UniProt: Q9BT25