UVSSA/KIAA1530 antibody (N-Term)

Catalog No. ABIN7465934

Product Details anti-UVSSA/KIAA1530 Antibody

Target: UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))

Binding Specificity: N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UVSSA/KIAA1530 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary.

Clone: GT816

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa , A375

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for UVSSA/KIAA1530

Target: UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))

Alternative Name: UV stimulated scaffold protein A (UVSSA Products)

Synonyms: KIAA1530 antibody, UVSS3 antibody, kiaa1530 antibody, 4933407H18Rik antibody, D330017J19Rik antibody, Kiaa1530 antibody, mKIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSSA antibody, uvssa antibody, Uvssa antibody

Background: UV stimulated scaffold protein A , KIAA1530 , UVSS3,The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Molecular Weight: 81 kDa

Gene ID: 57654

UniProt: Q2YD98