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Strumpellin antibody (C-Term)

WASHC5 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7465862
  • Target See all Strumpellin (WASHC5) Antibodies
    Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 4
    • 4
    • 2
    Human
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This Strumpellin antibody is un-conjugated
    Application
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human Strumpellin. The exact sequence is proprietary.
    Isotype
    IgG
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  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HeLa

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))
    Alternative Name
    WASH complex subunit 5 (WASHC5 Products)
    Synonyms
    SPG8 antibody, AL022848 antibody, C76463 antibody, Kiaa0196 antibody, mKIAA0196 antibody, strumpellin antibody, WASH complex subunit 5 antibody, WASHC5 antibody, washc5 antibody, Washc5 antibody
    Background
    WASH complex subunit 5 , KIAA0196 , RTSC , RTSC1 , SPG8,This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease, a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases. [provided by RefSeq]
    Molecular Weight
    134 kDa
    Gene ID
    9897
    UniProt
    Q12768
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