FBLIM1 antibody

Catalog No. ABIN7465769

Product Details anti-FBLIM1 Antibody

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FBLIM1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Alternative Name: filamin binding LIM protein 1 (FBLIM1 Products)

Synonyms: FBLIM1 antibody, CAL antibody, FBLP-1 antibody, FBLP1 antibody, 2410043F08Rik antibody, Cal antibody, Fblp1 antibody, Gt10 antibody, migfilin antibody, migfilin(s) antibody, filamin binding LIM protein 1 antibody, filamin binding LIM protein 1 S homeolog antibody, FBLIM1 antibody, fblim1.S antibody, Fblim1 antibody

Background: Filamin binding LIM protein 1 , CAL , FBLP-1 , FBLP1,This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Molecular Weight: 41 kDa

Gene ID: 54751

UniProt: Q8WUP2